Lilei Te (力雷特)力雷特
This is a medicine registration record from NMPA data.本页为国家药监局药品注册记录。
Labeled sections from the recorded Chinese source are included below. English wording is a reference translation when one is on file, not an official English label.本记录未接入产品级适应症/安全性标注字段。
生产企业Manufacturer
- 甘肃大得利制药有限公司Chinese legal name: 甘肃大得利制药有限公司
主要成分Active Ingredients
- 亚叶酸钙CF
药物知识说明
亚叶酸钙是一种在国家药监局注册认定的药品。该药品含有亚叶酸钙-8f402481等成分。
该药品关联的活性成分包括：亚叶酸钙Yaye Suangai。这些成分信息来自国家药监局数据库。
该药品标注的生产企业为：甘肃大得利制药有限公司Chinese legal name: 甘肃大得利制药有限公司。
您可以探索含有相同成分的其他药品：亚叶酸钙-8f402481成分药品。
本页面内容来自国家药监局数据库，MedicineGraph在此基础上提供关系图谱和知识导航。
Medicine Knowledge
This medicine (original name: 力雷特) is a medicine registered with the national drug regulatory authority. It contains recorded ingredients as active ingredient(s).
Active ingredients associated with this product: 亚叶酸钙Yaye Suangai.
Manufacturers recorded for this product: 甘肃大得利制药有限公司Chinese legal name: 甘肃大得利制药有限公司.
Explore other medicines containing the same ingredient: 亚叶酸钙 productsProducts containing this recorded ingredient.
Source: MedicineGraph authoritative database. Relationships derived from registered product information.
这是什么What is this
- 通用名/品名Recorded product name: 力雷特Recorded Chinese name: 力雷特
- 剂型Dosage form: 注射剂Injection
- 规格Specification: 50ml:亚叶酸钙0.05g与氯化钠0.45gRecorded Chinese specification: 50ml:亚叶酸钙0.05g与氯化钠0.45g
本段仅展示注册/说明书已记录的身份属性，不含适应症或用法建议。Identity attributes from registration/leaflet records only; no indications or usage advice.
主要成分Ingredients
生产企业Manufacturer
- 甘肃大得利制药有限公司Chinese legal name: 甘肃大得利制药有限公司
注册信息NMPA approval number
- 批准文号NMPA approval number: 国药准字H20050076
信息来源Source and scope
国家药品监督管理局（中国）药品注册数据及已接入说明书字段。National Medical Products Administration (China) medicine-registration data and linked leaflet fields.
- 品名来源Name source: 10多万条药品说明书数据库 (HIGH)Package-insert database (more than 100,000 records) (HIGH)
- 生产企业来源Manufacturer source: 10多万条药品说明书数据库Package-insert database (more than 100,000 records)
- 剂型来源Dosage-form source: 10多万条药品说明书数据库Package-insert database (more than 100,000 records)
范围：当前 MedicineGraph 注册记录及已记录的精确关系；非完整目录，亦不构成疗效等同主张，也不支持换用判断。不含适应症/安全性推断。Scope: current MedicineGraph registration records and exact recorded relationships; not a complete catalog and not a claim of therapeutic equivalence. No inferred indications/safety.
本段为已核准说明书原文摘录（非改写、非AI摘要），非正式英文标签，亦不构成用药建议。 Not an official English label and not medical advice. English wording, when shown, is a reference translation of the Chinese source label.
English translation for reference. Translated from the Chinese source label. Not an official English label and not medical advice.
NMPA approval number
国药准字H20050076
Manufacturer
Chinese legal name: 甘肃大得利制药有限公司 (domestically manufactured)
Indications
English translation unavailable. The original Chinese source label remains available below.
Dosage and administration
English translation unavailable. The original Chinese source label remains available below.
Adverse reactions
English translation unavailable. The original Chinese source label remains available below.
Contraindications
English translation unavailable. The original Chinese source label remains available below.
Precautions
English translation unavailable. The original Chinese source label remains available below.
Storage
English translation unavailable. The original Chinese source label remains available below.
Specification
English translation unavailable. The original Chinese source label remains available below.
中文说明书原文Original Chinese source label
批准文号
国药准字H20050076
生产企业
甘肃大得利制药有限公司(国产)
适应症
1.尿嘧啶合用,可提高氟尿嘧啶的疗效,临床上常用于结直肠癌与胃癌的治疗。|2.作叶酸拮抗剂(如甲氨蝶呤、乙胺嘧啶或甲氧苄啶等)的解毒剂，本品临床常用于预防甲氨蝶呤过量等大剂量治疗后所引起的严重毒性作用。|3.当口服叶酸疗效不佳时,用于口炎性腹泻、营养不良、妊娠期或婴儿期引起的巨幼细胞性贫血。
用法用量
1.用于与5-Fu合用增效:亚叶酸钙每次200mg/m2，静滴2小时，接着连续2天给予5-FU400mg/m2，每2周一次。|2.作为甲氨喋呤的“解救”疗法，本品剂量最好根据血药浓度而定，当甲氨喋呤用量为500mg/m2时，亚叶酸钙的一般剂量为100-500mg/m2，静注，每6小时1次，至甲氨喋呤血药浓度小于0.5μmol/l。
不良反应
很少见，偶见皮疹、荨麻疹或哮喘等其他过敏反应。
禁忌
1.已知对本品成份过敏者禁用。|2.恶性贫血或维生素B12缺乏所引起的巨幼红细胞性贫血禁用。
注意事项
1.当患者有下列情况者，本品应谨慎用于甲氨喋呤的“解救”治疗:酸性尿(pH<7)?腹水、失水、胃肠道梗阻、胸腔渗液或肾功能障碍，有上述情况时，甲氨喋呤毒性较显著，且不易从体内排出;病况急需者，本品剂量要加大。|2.接受大剂量甲氨喋呤而用本品“解救”者应进行下列各种实验监察：|(1)治疗前观察肌酐廓清试验。|(2)甲氨喋呤大剂量后每12～24小时测定血浆或血清甲氨喋呤浓度，以调整本品剂量;当甲氨喋呤浓度低于510-8mol/L时，可以停止实验室监察。|(3)甲氨喋呤治疗前及以后每24小时测定血清肌酐量，用药后24小时肌酐量大于治疗前50%，指示有严重肾毒性，要慎重处理。|(4)甲氨喋呤用药前和用药后每6小时应监察尿液酸度，要求尿液pH保持在7以上，必要时用碳酸氢钠和水化治疗(每日补液量在3000ml/m2)。|(5)本品不宜与甲氨喋呤同时用，以免影响后者抗叶酸作用，一次大剂量甲氨喋呤后24～48小时再启用本品，剂量应要求血药浓度等于或大于甲氨喋呤浓度。|3.对维生素B12缺乏所致的贫血不宜单用本品。
贮藏
遮光，2－8℃保存。有效期暂定12个月。
规格
50ml:亚叶酸钙0.05g与氯化钠0.45g
信息来源Source and scope
国家药品监督管理局（中国）药品注册数据。National Medical Products Administration (China) medicine-registration data.
范围：当前 MedicineGraph 注册记录及已记录的精确关系；非完整目录，亦不构成疗效等同主张，也不支持换用判断。Scope: current MedicineGraph registration records and exact recorded relationships; not a complete catalog and not a claim of therapeutic equivalence.