Zhi Le (之乐)之乐
This is a medicine registration record from NMPA data.本页为国家药监局药品注册记录。
Labeled sections from the recorded Chinese source are included below. English wording is a reference translation when one is on file, not an official English label.本记录未接入产品级适应症/安全性标注字段。
生产企业Manufacturer
- 齐鲁制药有限公司Chinese legal name: 齐鲁制药有限公司
主要成分Active Ingredients
- 普罗布考Puluo Bukao
药物知识说明
普罗布考是一种在国家药监局注册认定的药品。标注生产企业为齐鲁制药有限公司。
该药品暂无关联的活性成分信息。
该药品标注的生产企业为：齐鲁制药有限公司Chinese legal name: 齐鲁制药有限公司、齐鲁制药有限公司Chinese legal name: 齐鲁制药有限公司、齐鲁制药有限公司Chinese legal name: 齐鲁制药有限公司。
本页面内容来自国家药监局数据库，MedicineGraph在此基础上提供关系图谱和知识导航。
Medicine Knowledge
This medicine (original name: 之乐) is a medicine registered with the national drug regulatory authority. It is manufactured by Chinese legal name: 齐鲁制药有限公司.
No active ingredient relationships are currently recorded for this product in MedicineGraph.
Manufacturers recorded for this product: 齐鲁制药有限公司Chinese legal name: 齐鲁制药有限公司, 齐鲁制药有限公司Chinese legal name: 齐鲁制药有限公司, 齐鲁制药有限公司Chinese legal name: 齐鲁制药有限公司.
Source: MedicineGraph authoritative database. Relationships derived from registered product information.
这是什么What is this
- 通用名/品名Recorded product name: 之乐Recorded Chinese name: 之乐
- 剂型Dosage form: 片剂Tablets
- 规格Specification: 0.125g*32片0.125 g × 32 tablets
本段仅展示注册/说明书已记录的身份属性，不含适应症或用法建议。Identity attributes from registration/leaflet records only; no indications or usage advice.
生产企业Manufacturer
- 齐鲁制药有限公司Chinese legal name: 齐鲁制药有限公司
注册信息NMPA approval number
- 批准文号NMPA approval number: 国药准字H10980054
关联实体Relationships
信息来源Source and scope
国家药品监督管理局（中国）药品注册数据及已接入说明书字段。National Medical Products Administration (China) medicine-registration data and linked leaflet fields.
- 品名来源Name source: 10多万条药品说明书数据库 (HIGH)Package-insert database (more than 100,000 records) (HIGH)
- 生产企业来源Manufacturer source: 10多万条药品说明书数据库Package-insert database (more than 100,000 records)
- 剂型来源Dosage-form source: 10多万条药品说明书数据库Package-insert database (more than 100,000 records)
范围：当前 MedicineGraph 注册记录及已记录的精确关系；非完整目录，亦不构成疗效等同主张，也不支持换用判断。不含适应症/安全性推断。Scope: current MedicineGraph registration records and exact recorded relationships; not a complete catalog and not a claim of therapeutic equivalence. No inferred indications/safety.
本段为已核准说明书原文摘录（非改写、非AI摘要），非正式英文标签，亦不构成用药建议。 Not an official English label and not medical advice. English wording, when shown, is a reference translation of the Chinese source label.
English translation for reference. Translated from the Chinese source label. Not an official English label and not medical advice.
NMPA approval number
国药准字H10980054
Manufacturer
Chinese legal name: 齐鲁制药有限公司 (domestically manufactured)
Indications
English translation unavailable. The original Chinese source label remains available below.
Dosage and administration
English translation unavailable. The original Chinese source label remains available below.
Adverse reactions
English translation unavailable. The original Chinese source label remains available below.
Contraindications
English translation unavailable. The original Chinese source label remains available below.
Precautions
English translation unavailable. The original Chinese source label remains available below.
Storage
English translation unavailable. The original Chinese source label remains available below.
Specification
0.125 g × 32 tablets
中文说明书原文Original Chinese source label
批准文号
国药准字H10980054
生产企业
齐鲁制药有限公司(国产)
适应症
本品用于治疗高胆固醇血症。
用法用量
成人常用量每次0.5g，每日2次，早、晚餐时服用。
不良反应
1.本品最常见的不良反应为胃肠道不适，腹泻的发生率大约为10%，还有胀气、腹痛、恶心和呕吐。
2.其他少见的反应有：头痛、头晕、感觉异常、失眠、耳鸣、皮疹、皮肤瘙痒等。
3.有报道发生过血管神经性水肿的过敏反应。
4.罕见的严重的不良反应有：心电图Q-T间期延长、室性心动过速、血小板减少等。
禁忌
1.对普罗布考过敏者禁用。
2.由于本品可引起心电图Q-T间期延长和严重室性心律失常，故在下列情况禁用：
(1)近期心肌损害，如新近心肌梗死者。
(2)严重室性心律失常，如心动过缓者。
(3)有心源性晕厥或有不明原因晕厥者。
(4)有Q-T间期延长者。
(5) 正在使用延长Q-T间期的药物;血钾或血镁过低者。
注意事项
1.服用本品对诊断有干扰:可使血氨基转移酶、胆红素、肌酸磷酸激酶、尿酸、尿素氮短暂升高。
2.服用本品期间应定期检查心电图Q-T间期。
3.服用三环类抗抑郁药及抗心律失常药和吩噻嗪类药物的患者服用本品发生心律失常的危险性大。
贮藏
遮光密闭，干燥处保存。
规格
0.125g*32片
信息来源Source and scope
国家药品监督管理局（中国）药品注册数据。National Medical Products Administration (China) medicine-registration data.
范围：当前 MedicineGraph 注册记录及已记录的精确关系；非完整目录，亦不构成疗效等同主张，也不支持换用判断。Scope: current MedicineGraph registration records and exact recorded relationships; not a complete catalog and not a claim of therapeutic equivalence.